Comparison of two delta-crystallin genes in the chicken.


Restriction endonuclease mapping and electron microscopy established that there are at least two nonallelic delta-crystallin genes in the chicken. The structure of a complete delta-crystallin gene has been deduced by analysis of five cloned fragments from the chicken genome. Fifteen intervening sequences compose approximately 80% of this gene; the other gene contains at least 14 intervening sequences. The mRNA gene sequences appear to be similar; at least 60% divergence was found between the intervening sequences of the two delta-crystallin genes. Insertions or deletions or both appear to be major events responsible for these differences.

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@article{Jones1980ComparisonOT, title={Comparison of two delta-crystallin genes in the chicken.}, author={Raymond E. Jones and Suraj P. Bhat and Mark Sullivan and Joram Piatigorsky}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1980}, volume={77 10}, pages={5879-83} }