Comparison of treatment with fluorinated glucocorticoids to the natural history of autoantibody-associated congenital heart block: retrospective review of the research registry for neonatal lupus.

@article{Saleeb1999ComparisonOT,
  title={Comparison of treatment with fluorinated glucocorticoids to the natural history of autoantibody-associated congenital heart block: retrospective review of the research registry for neonatal lupus.},
  author={Susan Saleeb and Joshua Abbott Copel and Deborah M. Friedman and Jill P. Buyon},
  journal={Arthritis and rheumatism},
  year={1999},
  volume={42 11},
  pages={2335-45}
}
OBJECTIVE To compare intervention with fluorinated glucocorticoids to the natural history of untreated congenital heart block (CHB) with respect to conduction abnormalities, associated effusions, ascites, and hydrops fetalis, and the requirement for a pacemaker. METHODS Records of all mothers enrolled in the Research Registry for Neonatal Lupus were reviewed. The cohort includes 47 mothers whose sera contain anti-SSA/Ro or anti-SSB/La antibodies, and their 50 offspring with CHB, in whom at… CONTINUE READING

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