Comparison of tracheal and nasal chondrocytes for tissue engineering of the trachea.

@article{Kojima2003ComparisonOT,
  title={Comparison of tracheal and nasal chondrocytes for tissue engineering of the trachea.},
  author={Koji Kojima and Lawrence J. Bonassar and Ronald Ignotz and Kamil Syed and Joaquin Cortiella and Charles A. Vacanti},
  journal={The Annals of thoracic surgery},
  year={2003},
  volume={76 6},
  pages={1884-8}
}
BACKGROUND This study was undertaken to evaluate the feasibility of creating engineered tracheal equivalents grown in the shape of cylindrical cartilaginous structures using sheep nasal cartilage-derived chondrocytes. We also tested sheep tracheal and nasal septum for cell yield and quality of the engineered cartilage each produced. METHODS Nasal septum and tracheal tissue were harvested from sheep. Chondrocytes from each were separately isolated from the tissues and suspended in culture… CONTINUE READING