Comparison of three whole genome amplification methods for detection of genomic aberrations in single cells

@article{Normand2016ComparisonOT,
  title={Comparison of three whole genome amplification methods for detection of genomic aberrations in single cells},
  author={E. Normand and Sadeem Qdaisat and W. Bi and C. Shaw and I. B. Van den Veyver and A. Beaudet and A. Breman},
  journal={Prenatal Diagnosis},
  year={2016},
  volume={36},
  pages={823 - 830}
}
  • E. Normand, Sadeem Qdaisat, +4 authors A. Breman
  • Published 2016
  • Biology, Medicine
  • Prenatal Diagnosis
  • Detection of genomic copy number abnormalities in a single cell using array comparative genomic hybridization (CGH) offers a promising non‐invasive alternative for prenatal diagnosis. Our objective was to compare three commercially available whole‐genome amplification (WGA) kits for their capacity to produce high quality DNA from single cells that is suitable for both molecular genotyping and array CGH. 
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