Comparison of three silver stains for demonstrating neurofibrillary tangles and neuritic plaques in brain tissue stored for long periods

@article{Wilcock2004ComparisonOT,
  title={Comparison of three silver stains for demonstrating neurofibrillary tangles and neuritic plaques in brain tissue stored for long periods},
  author={G. Wilcock and S. Matthews and T. Moss},
  journal={Acta Neuropathologica},
  year={2004},
  volume={79},
  pages={566-568}
}
  • G. Wilcock, S. Matthews, T. Moss
  • Published 2004
  • Materials Science, Medicine, Biology
  • Acta Neuropathologica
  • SummaryThree methods were compared to find a reliable method for demonstrating neurofibrillary tangles (NFTs) and neuritic plaques (NPs) in brain tissue stored for long periods in formalin or as paraffin blocks. The short-term fixation of tissue, e.g. up to 6 months in formalin does not usually present a problem using any of the three methods tried, e.g. Gallyas, modified Palmgren, or modified Bielschowsky, but once the time lengthens to 6 years or more the demonstration of NFTs and NPs is not… CONTINUE READING

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