Comparison of three commercial sparse-matrix crystallization screens.

  title={Comparison of three commercial sparse-matrix crystallization screens.},
  author={Jong Wei Wooh and Richard D. Kidd and Jennifer L. Martin and Bostjan Kobe},
  journal={Acta crystallographica. Section D, Biological crystallography},
  volume={59 Pt 4},
Sparse-matrix sampling using commercially available crystallization screen kits has become the most popular way of determining the preliminary crystallization conditions for macromolecules. In this study, the efficiency of three commercial screening kits, Crystal Screen and Crystal Screen 2 (Hampton Research), Wizard Screens I and II (Emerald BioStructures) and Personal Structure Screens 1 and 2 (Molecular Dimensions), has been compared using a set of 19 diverse proteins. 18 proteins yielded… CONTINUE READING