Comparison of the virulence of O:9,12 and O:4,5,12 Salmonella typhimurium his+ transductants for mice.

The purpose of these experiments was to determine whether qualitative differences in the O repeat unit of the lipopolysaccharide of pathogenic Salmonella species affected virulence for mice. O:4,5,12 and O:9,12 sister his+ transductants were derived from a virulent Salmonella typhimurium. Fermentation markers were introduced by transduction to differentiate… CONTINUE READING