Comparison of the transdermal absorption of nimesulide from three commercially available gel formulations.

@article{Dayal2002ComparisonOT,
  title={Comparison of the transdermal absorption of nimesulide from three commercially available gel formulations.},
  author={Pankaj Patrick Dayal and Narayanasamy Kanikkannan and Amarjit Singh and Mandip Sing},
  journal={Drug development and industrial pharmacy},
  year={2002},
  volume={28 3},
  pages={297-304}
}
Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) applied topically for a variety of conditions characterized by pain and inflammation. One of the aims of this study was to compare the permeation profile of nimesulide from the commercially available transdermal gel formulations across dermatomed porcine and human skin. The in vitro transdermal absorption of nimesulide formulations across porcine skin and human skin was studiedfor 24 hr using a continuous flow-through diffusion cell… CONTINUE READING