Comparison of the toxicity of smoke from conventional and harm reduction cigarettes using human embryonic stem cells.

@article{Lin2010ComparisonOT,
  title={Comparison of the toxicity of smoke from conventional and harm reduction cigarettes using human embryonic stem cells.},
  author={Sabrina Lin and Shawn Fonteno and Jo-Hao Weng and Prue Talbot},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2010},
  volume={118 1},
  pages={
          202-12
        }
}
This study evaluated the hypothesis that smoke from harm reduction cigarettes impedes attachment and proliferation of H9 human embryonic stem cells (hESCs). Smoke from three harm reduction brands was compared with smoke from a conventional brand. Doses of smoke were measured in puff equivalents (PE) (1 PE = the amount of smoke in one puff that dissolves in 1 ml of medium). Cytotoxic doses were determined using morphological criteria and trypan blue staining, and apoptosis was confirmed using… CONTINUE READING

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