Comparison of the temporal profile of calcineurin inhibition by cyclosporine and tacrolimus in renal transplant patients.

@article{KoefoedNielsen2005ComparisonOT,
  title={Comparison of the temporal profile of calcineurin inhibition by cyclosporine and tacrolimus in renal transplant patients.},
  author={P Koefoed-Nielsen and Nikolaos Karamperis and Kaj A. J\orgensen},
  journal={Transplantation proceedings},
  year={2005},
  volume={37 4},
  pages={1736-8}
}
Calcineurin phosphatase (CaN) activity has been the focus of several recent studies on renal transplant patients as the calcineurin inhibitors tacrolimus (FK) and cyclosporine (CsA) are still the cornerstone in the immunosuppressive treatment. The aim of this study was to compare the temporal inhibition profiles of CaN using CsA or FK in two groups of renal transplant patients. Nineteen tacrolimus-treated and 10 cyclosporine-treated renal transplant patients had blood samples drawn before and… CONTINUE READING