Comparison of the stimulus properties of a pre- vs. a putative postsynaptic dose of quinpirole.

@article{CorySlechta1996ComparisonOT,
  title={Comparison of the stimulus properties of a pre- vs. a putative postsynaptic dose of quinpirole.},
  author={Deborah A. Cory-Slechta and Christina L. Zuch and Robert A. Fox},
  journal={Pharmacology, biochemistry, and behavior},
  year={1996},
  volume={55 3},
  pages={423-32}
}
Presynaptic D2-like receptors appear to mediate the stimulus properties of a low dose (0.05 mg/kg) of the D2-like agonist quinpirole (QUIN), because treatments decreasing dopamine (DA) release or blocking postsynaptic DA receptor activation produce QUIN-appropriate responding in a drug discrimination context, whereas treatments activating postsynaptic DA receptors evoke saline responding (28). This study examined the hypothesis that training to a presumably postsynaptic dose of QUIN (0.20 mg/kg… CONTINUE READING
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