Comparison of the respiratory responses to external resistive loading and bronchoconstriction.

@article{Kelsen1981ComparisonOT,
  title={Comparison of the respiratory responses to external resistive loading and bronchoconstriction.},
  author={Steven G Kelsen and T F Prestel and Neil S. Cherniack and Edward H. Chester and E C Deal},
  journal={The Journal of clinical investigation},
  year={1981},
  volume={67 6},
  pages={1761-8}
}
The effects of resistive loads applied at the mouth were compared to the effects of bronchospasm on ventilation, respiratory muscle force (occlusion pressure), and respiratory sensations in 6 normal and 11 asthmatic subjects breathing 100% O2. External resistive loads ranging from 0.65 to 13.33 cm H2O/liter per s were applied during both inspiration and expiration. Bronchospasm was induced by inhalation of aerosolized methacholine. Bronchospasm increased ventilation, inspiratory airflow… CONTINUE READING