Comparison of the reactions induced by psilocybin and LSD-25 in man

@article{Isbell1959ComparisonOT,
  title={Comparison of the reactions induced by psilocybin and LSD-25 in man},
  author={Harris Isbell},
  journal={Psychopharmacologia},
  year={1959},
  volume={1},
  pages={29-38}
}
1. The reaction induced by oral administration of 57 to 114 mcgm/kg of 0-Phosphoryl-4-hydroxy-N-dimethyltryptamine (psilocybin) has been compared with that induced by a placebo and LSD-25 (1.0 to 1.5 mcgm/kg) in 9 subjects. 2. Both LSD and psilocybin caused elevations in body temperature, pulse and respiratory rates, and systolic blood pressure. Threshold for elicitation of the kneejerk was decreased by both drugs. 3. After both drugs, abnormal mental states characterized by feelings of… CONTINUE READING