Comparison of the radiotoxicity of the 99mTc-labeled compounds 99mTc-pertechnetate, 99mTc-HMPAO and 99mTc-MIBI.

@article{Maucksch2016ComparisonOT,
  title={Comparison of the radiotoxicity of the 99mTc-labeled compounds 99mTc-pertechnetate, 99mTc-HMPAO and 99mTc-MIBI.},
  author={Ute Maucksch and Roswitha Runge and Gerd Wunderlich and Robert Freudenberg and Anne Naumann and J{\"o}rg Kotzerke},
  journal={International journal of radiation biology},
  year={2016},
  volume={92 11},
  pages={698-706}
}
PURPOSE In addition to gamma radiation, 99mTc emits low-energy Auger electrons with path-lengths of nanometers to micrometers that cannot be utilized for diagnostic procedures; however, they have frequently been discussed for therapeutic applications. We compared radiotoxicity of three 99mTc-labeled radiopharmaceuticals with differences in the subcellular distribution. MATERIALS AND METHODS The intracellular radionuclide uptake and subcellular distribution of [99mTc]-pertechnetate (99mTc… CONTINUE READING
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