Comparison of the properties of human CD146+ and CD146- periodontal ligament cells in response to stimulation with tumour necrosis factor α.

@article{Zhu2013ComparisonOT,
  title={Comparison of the properties of human CD146+ and CD146- periodontal ligament cells in response to stimulation with tumour necrosis factor α.},
  author={Wenjun Zhu and Yuanyuan Tan and Qihong Qiu and Xiting Li and Zixian Huang and Yun Fu and M. -Z. Liang},
  journal={Archives of oral biology},
  year={2013},
  volume={58 12},
  pages={1791-803}
}
OBJECTIVES Periodontal ligament stem cells (PDLSCs) can be used in periodontal regeneration. Tumour necrosis factor-alpha (TNF-α) participates in the regulation of cell proliferation, apoptosis, differentiation, and migration. However, whether TNF-α can affect the biological features of PDLSCs is still unclear. The objective of this study was to illustrate the biological effects (proliferation, apoptosis, osteogenesis and migration) of TNF-α on human CD146 positive periodontal ligament cells… CONTINUE READING

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