Comparison of the neuromuscular blocking effect of cisatracurium and atracurium on the larynx and the adductor pollicis.

@article{Kirov2004ComparisonOT,
  title={Comparison of the neuromuscular blocking effect of cisatracurium and atracurium on the larynx and the adductor pollicis.},
  author={Krassen Kirov and Cyrus Motamed and François Decailliot and N. Behforouz and Philippe Duvaldestin},
  journal={Acta anaesthesiologica Scandinavica},
  year={2004},
  volume={48 5},
  pages={577-81}
}
BACKGROUND Cisatracurium unlike atracurium is devoid of histamine-induced cardiovascular effects and this alone would be the greatest advantage in replacing atracurium for the facilitation of tracheal intubation. On the other hand, 2 ED(95) doses of cisatracurium (100 micro g/kg) do not yield satisfactory intubating conditions such as those seen with equipotent doses of atracurium and therefore the recommended intubating dose of cisatracurium is 3 ED(95). To understand this discrepancy better… CONTINUE READING
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