Comparison of the inhibition by glucocorticosteroids and cyclosporin A of mitogen-stimulated human lymphocyte proliferation.

@article{Gordon1981ComparisonOT,
  title={Comparison of the inhibition by glucocorticosteroids and cyclosporin A of mitogen-stimulated human lymphocyte proliferation.},
  author={David Gordon and Ali Mohammad Nouri},
  journal={Clinical and experimental immunology},
  year={1981},
  volume={44 2},
  pages={287-94}
}
We examined the effects of dexamethasone, hydrocortisone and cyclosporin A (CyA), alone and in combination, on tritiated thymidine (3H-TdR) incorporation into human blood mononuclear cells stimulated by phytohaemagglutinin (PHA), pokeweed mitogen (PWM) and phorbol myristic acetate (PMA). Pharmacological concentrations of glucocorticosteroids displaced the… CONTINUE READING