Comparison of the influenza virus-specific effector and memory B-cell responses to immunization of children and adults with live attenuated or inactivated influenza virus vaccines.

@article{Sasaki2007ComparisonOT,
  title={Comparison of the influenza virus-specific effector and memory B-cell responses to immunization of children and adults with live attenuated or inactivated influenza virus vaccines.},
  author={Sanae Sasaki and Mar{\'i}a C. Jaimes and Tyson H. Holmes and Cornelia L Dekker and Kutubuddin Mahmood and George W. Kemble and Ann Margaret Arvin and Harry B Greenberg},
  journal={Journal of virology},
  year={2007},
  volume={81 1},
  pages={215-28}
}
Cellular immune responses to influenza virus infection and influenza virus vaccination have not been rigorously characterized. We quantified the effector and memory B-cell responses in children and adults after administration of either live attenuated (LAIV) or inactivated (TIV) influenza virus vaccines and compared these to antibody responses. Peripheral blood mononuclear cells were collected at days 0, 7 to 12, and 27 to 42 after immunization of younger children (6 months to 4 years old… CONTINUE READING