Comparison of the immune profile of nonhealing cutaneous Leishmaniasis patients with those with active lesions and those who have recovered from infection.

@article{Ajdary2000ComparisonOT,
  title={Comparison of the immune profile of nonhealing cutaneous Leishmaniasis patients with those with active lesions and those who have recovered from infection.},
  author={Soheila Ajdary and Mohammad Hossein Alimohammadian and Mohammad Bagher Eslami and K. von Kemp and Arsalan Kharazmi},
  journal={Infection and immunity},
  year={2000},
  volume={68 4},
  pages={1760-4}
}
Th1-type cellular immune responses play a critical role in protection against infection with Leishmania parasites, whereas activation of Th2-type cells results in progressive disease. Cutaneous leishmaniasis caused by Leishmania major is often a self-healing disease; however, persistent nonhealing forms are also known. In the present study, we have described cell-mediated immune responses in nonhealing patients by measuring T-cell proliferation, cytokine production, and phenotypic… CONTINUE READING

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