Comparison of the functional results of single lung transplantation for pulmonary fibrosis and chronic airway obstruction.

@article{Chacon1998ComparisonOT,
  title={Comparison of the functional results of single lung transplantation for pulmonary fibrosis and chronic airway obstruction.},
  author={R A Chacon and Paul A. Corris and J. H. Dark and G. John Gibson},
  journal={Thorax},
  year={1998},
  volume={53 1},
  pages={
          43-9
        }
}
BACKGROUND Single lung transplantation (SLT) is now a treatment option for patients with both pulmonary fibrosis and advanced chronic airway obstruction. Lung function after transplantation might be expected to be different in these two groups of patients because of the effect of the remaining native lung, but the implications of these differences have not been fully explored. METHODS The functional results of a stable population of 20 patients (13 chronic airway obstruction, seven pulmonary… Expand
Maximal expiratory flow patterns after single-lung transplantation in patients with and without chronic airways obstruction.
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The view that this biphasic-plateau pattern in the maximal expiratory flow-volume (MEFV) curve is a result of airflow from the native and transplanted lungs in patients with chronic airways obstruction is supported. Expand
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  • Journal of applied physiology
  • 2009
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The effects of single-lung transplantation and lung volume reduction favorably impact on the disadvantageous size interaction by which the lungs are functionally restricted by the chest wall in emphysema. Expand
Bronchiolitis obliterans syndrome in single lung transplant recipients--patients with emphysema versus patients with idiopathic pulmonary fibrosis.
TLDR
The native lung physiology appears to influence lung function and therefore survival, and this may indicate that the classification of BOS should include disease-specific characteristics. Expand
Functional improvement in patients with idiopathic pulmonary fibrosis undergoing single lung transplantation *
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  • Medicine
  • Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia
  • 2015
TLDR
Single lung transplantation in IPF patients who survive for at least one year provides significant and progressive benefits in lung function during the first year, and this procedure is an important therapeutic alternative in the management of IPF. Expand
Single-breath test in lateral decubitus reflects function of single lungs grafted for interstitial lung disease.
TLDR
It is concluded that, in patients with SLT for ILD, the slope of the alveolar plateau obtained with the graft in the nondependent position reflects heterogeneity of ventilation distribution in this lung. Expand
Ventilation asymmetry after transplantation for emphysema: role of chest wall and mediastinum.
TLDR
The two hemithoraces assume identical static volumes and show similar volume changes during CO(2)-induced hyperpnea and FVC maneuvers in patients with single-lung transplantation for emphysema; displacement of the mediastinum accommodates part, if not all, of the unequal lung volumes and asymmetrical ventilation. Expand
Tests of airway function in detecting and monitoring treatment of obliterative bronchiolitis after lung transplantation.
  • R. Chacon, P. Corris, J. Dark, G. Gibson
  • Medicine
  • The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
  • 2000
TLDR
The results support the use of simple spirometric indices for the detection of OB in patients with and without obliterative bronchiolitis after heart lung and lung transplantation. Expand
Lung transplantation and lung volume reduction surgery.
TLDR
An overview of the clinical aspects of these procedures, including patient selection, surgical techniques, complications, and outcomes, is provided and the insights from the last 15 years on the mechanisms whereby removal of lung from an emphysema patient can improve the function of the lung left behind are reviewed. Expand
Volume of graft and native lung after single-lung transplantation for emphysema.
TLDR
The TLC of the graft and of the native lung do not change over time after SLT for emphysema, and compared with the ipsilateral lung in normal control subjects, the TLC is substantially reduced, but its FRC is within normal limits. Expand
Effects of single‐lung inflation on inspiratory muscle function in dogs
TLDR
In patients with SLT for emphysema, the inspiratory ΔPpl over the transplanted lung are greater than those over the native lung and this difference results primarily from the greater pressure‐generating ability of the inspiratories muscles, in particular the diaphragm, on the transplants side. Expand
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