Comparison of the effects of three indirect dopamine agonists, GK 13, GBR 12783 and dexamphetamine on behavioural tests involving central catecholaminergic transmissions

@article{DuterteBoucher2005ComparisonOT,
  title={Comparison of the effects of three indirect dopamine agonists, GK 13, GBR 12783 and dexamphetamine on behavioural tests involving central catecholaminergic transmissions},
  author={D. Duterte-Boucher and Jean Marc Kamenka and Jean Costentin},
  journal={Psychopharmacology},
  year={2005},
  volume={101},
  pages={344-353}
}
  • D. Duterte-Boucher, Jean Marc Kamenka, Jean Costentin
  • Published 2005
  • Psychology, Medicine
  • Psychopharmacology
  • GK 13 (N-[1-(2-benzo (b) thiophenyl)-cyclohexyl] piperidine), GBR 12783 (1-[2-(diphenylmethoxy)ethyl] 4-(3-phenyl propenyl)-piperazine and dexamphetamine are three indirect catecholaminergic agonists, acting via different neurochemical mechanisms. We have compared their effects in rodents, in several behavioral tests. All three drugs increased locomotion. The stimulant locomotor effect of dexamphetamine was more easily antagonized by haloperidol than that of GBR 12783 and GK 13. Only… CONTINUE READING

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