Comparison of the effects of synthetic human parathyroid hormone (PTH)-(1-34)-related peptide of malignancy and bovine PTH-(1-34) on bone formation and resorption in organ culture.

Abstract

We have compared the effects of synthetic amino-terminal human PTH-(1-34)-related peptide (PTHrP) of malignancy with those of synthetic bovine PTH-(1-34) in cultures of half-calvariae from 21-day-old fetal rats and of parietal bones from 7-day neonatal mice. Incorporation of [3H] proline into collagenase-digestible protein (CDP) and noncollagen protein (NCP… (More)

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