Comparison of the effects of prototypical behavioral stimulants on locomotor activity and rotational behavior in rats.

@article{Garrett1996ComparisonOT,
  title={Comparison of the effects of prototypical behavioral stimulants on locomotor activity and rotational behavior in rats.},
  author={B E Garrett and Stephen G. Holtzman},
  journal={Pharmacology, biochemistry, and behavior},
  year={1996},
  volume={54 2},
  pages={469-77}
}
The present study was performed to characterize on rotational behavior the dose- and time-effect relationship of four prototypical behavioral stimulants that interact with dopamine systems via different mechanisms of action. Drug effects on rotational behavior was compared with effects on locomotor activity. The drugs examined were apomorphine (0.03-1.0 mg/kg), d-amphetamine (0.1-3.0 mg/kg), cocaine (3.0-56 mg/kg), and caffeine (10-100 mg/kg). SKF-38393 (0.3-10 mg/kg), a dopamine receptor… CONTINUE READING

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