Comparison of the effects of growth hormone, insulin-like growth factor-I and fetal calf serum on mouse molar odontogenesis in vitro.

@article{Young1995ComparisonOT,
  title={Comparison of the effects of growth hormone, insulin-like growth factor-I and fetal calf serum on mouse molar odontogenesis in vitro.},
  author={William George Young and Jean Victor Ruch and Mikel R. Stevens and C B{\'e}gue-Kirn and Chayvis Z. Zhang and Herv{\'e} Lesot and Michael J. Waters},
  journal={Archives of oral biology},
  year={1995},
  volume={40 9},
  pages={789-99}
}
The effects of growth hormone, its mediator insulin-like growth factor-I (IGF-I), and fetal calf serum on odontogenesis were compared to those of serum-free medium. Explanted, 16-day, fetal mouse first molar tooth germs in early bell stage were grown on semisolid, serum-free medium supplemented with ascorbic and retinoic acids. Recombinant human growth hormone at 50 or 100 ng/ml, IGF-I at 100 or 200 ng/ml, or fatal calf serum at 20% concentration were added to the media. Volumetric changes in… CONTINUE READING

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