Comparison of the effects of disodium ethylenediaminetetraacetate, theophylline, and deoxycholic acid on colonic ion transport and permeability.

Abstract

The effects of ethylenediaminetetraacetate (EDTA), theophylline, and deoxycholic acid (DCA) on colonic ion transport and permeability were examined in an isolated loop system of the pig colon. The 3 agents abolished net water absorption, but only EDTA and DCA induced an increase in mucosal permeability. Theophylline resulted in active bicarbonate secretion… (More)

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