Comparison of the effects of cholic acid and chenic acid feeding on rates of cholesterol synthesis in the liver of the rat

Abstract

To compare the ability of cholic acid and chenic acid to suppress cholesterol synthesis in the liver, these two bile acids were fed in varying amounts to rats for either 66 hr or 6 weeks. In both instances there were significant changes in the bile acid pool in the small intestine and suppression of the rate of cholesterol synthesis in the liver. The… (More)
DOI: 10.1007/BF01072189

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