Comparison of the effects of adrenergic agonists and alpha-, beta 1-, beta 2-antagonists on the intraocular pressure and adenylate cyclase activity in the ciliary processes of the rabbit.

@article{Palkama1985ComparisonOT,
  title={Comparison of the effects of adrenergic agonists and alpha-, beta 1-, beta 2-antagonists on the intraocular pressure and adenylate cyclase activity in the ciliary processes of the rabbit.},
  author={Arto Palkama and H. Uusitalo and K A Raij and Risto J. Uusitalo},
  journal={Acta ophthalmologica},
  year={1985},
  volume={63 1},
  pages={9-15}
}
The hypotensive effect of different adrenergic agonists and antagonists were screened both in normo- and hypertensive rabbit eyes. The drugs were applicated topically and intraocular pressure (IOP) was monitored constantly with a manometric method. Subsequently the inhibitory effect of the antagonists on isoproterenol-stimulated adenylate cyclase activity… CONTINUE READING