Comparison of the contractile and calcium-increasing properties of platelet-activating factor and endothelin-1 in the rat mesenteric artery and vein.

@article{Claing2002ComparisonOT,
  title={Comparison of the contractile and calcium-increasing properties of platelet-activating factor and endothelin-1 in the rat mesenteric artery and vein.},
  author={Audrey Claing and Hadia Shbaklo and Mirco Plante and Ghassan B Bkaily and Pedro D'Orl{\'e}ans-Juste},
  journal={British journal of pharmacology},
  year={2002},
  volume={135 2},
  pages={433-43}
}
In the present study, the properties of endothelin-1 (ET-1) and platelet-activating factor (PAF) in inducing contraction and increased intracellular-free calcium level in rat mesenteric arteries and veins were studied. Furthermore, measurements of cytosolic ([Ca](c)) and nuclear ([Ca](n)) Ca(2+) were performed by confocal microscopy. PAF, at a concentration… CONTINUE READING