Comparison of the clinical utility of the Elia CTD Screen to indirect immunofluorescence on Hep-2 cells.

@article{Robier2016ComparisonOT,
  title={Comparison of the clinical utility of the Elia CTD Screen to indirect immunofluorescence on Hep-2 cells.},
  author={C Robier and Omid Amouzadeh-Ghadikolai and Mariana Stettin and Gerhard Reicht},
  journal={Clinical chemistry and laboratory medicine},
  year={2016},
  volume={54 8},
  pages={1365-70}
}
BACKGROUND We compared the Elia CTD Screen (ECS), a fluoroenzymeimmunoassay incorporating 17 human antinuclear antigens (ANA), with indirect immunofluorescence (IIF) on Hep-2 cells in order to determine the clinical utility of the ECS in additon to or without IIF. METHODS We examined 1708 consecutive serum samples submitted for ANA testing using the ECS and IIF in parallel. Positive screen results were further examined by quantitative fluoroenzymeimmunoassays and/or immunoblots for antibody… CONTINUE READING
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