Comparison of the calcium entry and calcium overload blocking properties of R71811 and flunarizine

The effects of several calcium antagonists on cell death induced by A23187 were studied. Furthermore, R71811,1-[Bis(4-fluorophenyl)methyl-4-(4-methoxyphenyl)-carbamoylmethyl-trans-2,5-dimethyl-piperazine has been evaluated as a calcium overload blocker and compared to flunarizine. The viability of cultured glial cells was decreased by incubation with the… CONTINUE READING