Comparison of the biological characteristics of two isolates of Neospora caninum.

@article{Atkinson1999ComparisonOT,
  title={Comparison of the biological characteristics of two isolates of Neospora caninum.},
  author={Rebecca K. Atkinson and Patricia A. Harper and Cheryl Ryce and David A. Morrison and John T. Ellis},
  journal={Parasitology},
  year={1999},
  volume={118 ( Pt 4)},
  pages={363-70}
}
This study compared the biological and genetic properties of a bovine (NC-SweB1) and a canine (NC-Liverpool) isolate of Neospora caninum. A mouse model for CNS infection demonstrated marked differences in pathogenicity between the isolates. NC-Liverpool induced severe clinical signs of neosporosis in 57/58 mice including discoordinated movement, hindlimb paralysis and coat ruffling with severe weight loss. In contrast NC-SweB1 induced similar but less severe symptoms in a much smaller… CONTINUE READING