Comparison of the biochemical responses to human parathyroid hormone-(1-31)NH2 and hPTH-(1-34) in healthy humans.

@article{Fraher1999ComparisonOT,
  title={Comparison of the biochemical responses to human parathyroid hormone-(1-31)NH2 and hPTH-(1-34) in healthy humans.},
  author={Laurence J. Fraher and Ramona Avram and Patricia H Watson and Geoffrey N Hendy and Janet E. Henderson and Karen S L Chong and David Goltzman and P. D. Morley and Gordon E. Willick and James F. Whitfield and Anthony B. Hodsman},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1999},
  volume={84 8},
  pages={2739-43}
}
The 1-31 fragment of human PTH [hPTH-(1-31)NH2] has been shown, like hPTH-(1-34), to have anabolic effects on the skeletons of ovariectomized rats when given intermittently, but, unlike hPTH-(1-34), it does so without affecting serum calcium concentrations and does not activate the protein kinase C second messenger pathway in some target cells. To… CONTINUE READING