Comparison of the bactericidal activity of trovafloxacin and ciprofloxacin, alone and in combination with cefepime, against Pseudomonas aeruginosa.

@article{McNabb2000ComparisonOT,
  title={Comparison of the bactericidal activity of trovafloxacin and ciprofloxacin, alone and in combination with cefepime, against Pseudomonas aeruginosa.},
  author={JoCarol J McNabb and Richard Quintiliani and Charles H. Nightingale and David P Nicolau},
  journal={Chemotherapy},
  year={2000},
  volume={46 6},
  pages={383-9}
}
BACKGROUND Although ciprofloxacin exhibits more intense microbiological activity against Pseudomonas aeruginosa than does trovafloxacin, the clinical relevance of this observation remains questionable, particularly when the agents are combined with another antipseudomonal agent. METHODS To evaluate this further, we conducted a four-way crossover trial to… CONTINUE READING