Comparison of the acute toxicity of clioquinol, histamine, and chloroform in different strains of mice.

@article{Pericin1979ComparisonOT,
  title={Comparison of the acute toxicity of clioquinol, histamine, and chloroform in different strains of mice.},
  author={C. Pericin and Peter Thomann},
  journal={Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement},
  year={1979},
  volume={2},
  pages={371-3}
}
The oral LD50'S of clioquinol, histamine and chloroform and the intravenous LD50 of histamine were determined separately in male and female mice of the Tif : MAGf (SPF), Tif : MF2f (SPF), C3H/Tif Bomf, DBA2/J Bomf, C57Bl/6J/Bomf and A/J Bomf strains. Mice of the Tif : MAGf (SPF) outbred strain and the Tif : MF2f(SPF) hybrids tended to be more resistant than the inbred strains, with exception of C57Bl/6J/Bomf, which proved least susceptible to the lethal effects of the tested preparations. The… CONTINUE READING