Comparison of the acute effects of ethanol on liver and skeletal muscle protein synthesis in the rat.

@article{Preedy1988ComparisonOT,
  title={Comparison of the acute effects of ethanol on liver and skeletal muscle protein synthesis in the rat.},
  author={Victor R. Preedy and P B Duane and Timothy J. Peters},
  journal={Alcohol and alcoholism},
  year={1988},
  volume={23 2},
  pages={155-62}
}
(1) The acute effects of ethanol on protein synthesis by liver and skeletal muscle were investigated in young (95-100 g) rats. Rats were injected intraperitoneally with ethanol, 75 mmol/kg body wt; controls were injected with isovolumetric 0.15 M NaCl. After 140 min rates of protein synthesis were measured by injection of a large dose of L[4(3)H]phenylalanine and at 150 min rats were killed. (2) Fractional rates of protein synthesis in control animals were approximately four to five times… CONTINUE READING