Comparison of the Semisolid Agar Antifungal Susceptibility Test with the NCCLS M38-P Broth Microdilution Test for Screening of Filamentous Fungi

  title={Comparison of the Semisolid Agar Antifungal Susceptibility Test with the NCCLS M38-P Broth Microdilution Test for Screening of Filamentous Fungi},
  author={Çiğdem Kuzucu and Barbara Rapino and Laura Mcdermott and Susan Hadley},
  journal={Journal of Clinical Microbiology},
  pages={1224 - 1227}
ABSTRACT Antifungal susceptibility testing of pathogenic molds is being developed. A simple screening semisolid agar antifungal susceptibility (SAAS) test accurately measures susceptibilities of yeasts. The performance of the SAAS screening test for filamentous fungi was assessed by comparing MICs of four antifungals (amphotericin B [AMB], AMB lipid complex [ABEL], itraconazole [ITZ], and posaconazole [POS]) for 54 clinical mold isolates with the results of the National Committee for Clinical… 
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Real-time antifungal susceptibility screening aids management of invasive yeast infections in immunocompromised patients.
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Has antifungal susceptibility testing come of age?
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Standardized susceptibility testing for selected organism-drug combinations has been shown to have similar predictive utility, and antifungal susceptibility testing is now increasingly and appropriately used as a routine adjunct to the treatment of fungal infections.
Spectrophotometric method of inoculum preparation for the in vitro susceptibility testing of filamentous fungi
Homogeneous inoculum suspensions of 29 isolates of clinically important filamentous fungi were adjusted with a spectrophotometer (530 nm) to obtain standardized preparations containing 1 x 10(6) to 5
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Rates of MC mortality for the different mycoses varied markedly according to human immunodeficiency virus (HIV) status but were consistently higher among males, blacks, and persons > or =65 years of age, highlighting the public health importance of mycotic diseases and emphasize the need for continuing surveillance.