Comparison of the Preventive Activity of Isorhamnetin Glycosides from Atsumi-kabu (Red Turnip, Brassica, campestris L.) Leaves on Carbon Tetrachloride-Induced Liver Injury in Mice

@article{Igarashi2008ComparisonOT,
  title={Comparison of the Preventive Activity of Isorhamnetin Glycosides from Atsumi-kabu (Red Turnip, Brassica, campestris L.) Leaves on Carbon Tetrachloride-Induced Liver Injury in Mice},
  author={Kiharu Igarashi and Tsuyoshi Mikami and Yuri Takahashi and Hideyo Sato},
  journal={Bioscience, Biotechnology, and Biochemistry},
  year={2008},
  volume={72},
  pages={856 - 860}
}
Isorhamnetin 3-O-glucoside, which was contained together with isorhamnetin 3,7-di-O-glucoside in atsumi-kabu leaves, suppressed increases in the plasma ALT and AST activities of mice with liver injury induced by the injection of carbon tetrachloride, but no suppression by isorhamnetin 3,7-di-O-glucoside was apparent. This result indicates that the release of glucose at the 7-position in isorhamnetin 3,7-di-O-glucoside was very important to mitigating liver injury. 
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