Comparison of the Papanicolaou and Feulgen staining methods for DNA quantification by image analysis.

@article{Gurley1990ComparisonOT,
  title={Comparison of the Papanicolaou and Feulgen staining methods for DNA quantification by image analysis.},
  author={A M Gurley and D F Hidvegi and James W. Bacus and Sarah S. Bacus},
  journal={Cytometry},
  year={1990},
  volume={11 4},
  pages={468-74}
}
The possibility of using archival cytology material to study the evolution of neoplastic disease with regard to DNA content abnormalities was investigated. The accuracy of measuring the integrity optical density (OD) of nuclei that correlates to DNA amounts of those nuclei, on slides stained by the Papanicolaou method, was assessed and compared with a standard Feulgen method. Our data on rat liver nuclei peritoneal washings from patients with ovarian cystadenofibromas and ovarian… CONTINUE READING

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