Comparison of the Long-term Effects of Liraglutide and Glimepiride Monotherapy on Bone Mineral Density in Patients with Type 2 Diabetes.

@article{Gilbert2016ComparisonOT,
  title={Comparison of the Long-term Effects of Liraglutide and Glimepiride Monotherapy on Bone Mineral Density in Patients with Type 2 Diabetes.},
  author={Matthew P Gilbert and Michel Marre and Jens Juul Holst and A. I. Garber and Florian M. M. Baeres and H. Gr\onlund Thomsen and Richard E. Pratley},
  journal={Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists},
  year={2016},
  volume={22 4},
  pages={406-11}
}
OBJECTIVE Patients with type 2 diabetes have an increased risk of fragility fractures; the cause is unclear but is likely multifactorial. Some diabetes treatments induce bone loss, accentuating underlying skeletal fragility and increasing fracture risk. This subgroup analysis aimed to compare long-term effects of liraglutide and glimepiride on bone mineral density (BMD) in patients with type 2 diabetes. METHODS LEAD-3, a 52-week, double-blind, active-control, phase III, multicenter trial… CONTINUE READING

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