Comparison of the Effects of l‐Carnitine and Acetyl‐l‐Carnitine on Carnitine Levels, Ambulatory Activity, and Oxidative Stress Biomarkers in the Brain of Old Rats

@article{Liu2004ComparisonOT,
  title={Comparison of the Effects of l‐Carnitine and Acetyl‐l‐Carnitine on Carnitine Levels, Ambulatory Activity, and Oxidative Stress Biomarkers in the Brain of Old Rats},
  author={Jiankang Liu and Elizabeth Head and Hirohiko Kuratsune and Carl Cotman and Bruce N. Ames},
  journal={Annals of the New York Academy of Sciences},
  year={2004},
  volume={1033}
}
Abstract: l‐Carnitine and acetyl‐l‐carnitine (ALC) are both used to improve mitochondrial function. Although it has been argued that ALC is better than l‐carnitine in absorption and activity, there has been no experiment to compare the two compounds at the same dose. In the present experiment, the effects of ALC and l‐carnitine on the levels of free, acyl, and total l‐carnitine in plasma and brain, rat ambulatory activity, and biomarkers of oxidative stress are investigated. Aged rats (23… 
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