Comparison of the Effects of Central and Peripheral Dopamine Receptor Activation on Evoked Firing in the Trigeminocervical Complex

@article{Charbit2009ComparisonOT,
  title={Comparison of the Effects of Central and Peripheral Dopamine Receptor Activation on Evoked Firing in the Trigeminocervical Complex},
  author={A. Charbit and S. Akerman and P. Goadsby},
  journal={Journal of Pharmacology and Experimental Therapeutics},
  year={2009},
  volume={331},
  pages={752 - 763}
}
  • A. Charbit, S. Akerman, P. Goadsby
  • Published 2009
  • Chemistry, Medicine
  • Journal of Pharmacology and Experimental Therapeutics
  • Dopaminergic mechanisms have been suggested to play a role in migraine. Here, electrophysiological techniques were used to study the effects of intravenously administered centrally or peripherally active dopamine receptor agonists and antagonists on evoked firing in the trigeminocervical complex (TCC). After establishing baseline firing evoked by electrical stimulation of the dural middle meningeal artery (MMA) and mechanical noxious and innocuous stimulation of the ophthalmic dermatome, D1- or… CONTINUE READING
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