Comparison of the Effects of Bretylium, Guanethidine and Bethanidine on Smooth Muscle Responses to Different Rates of Sympathetic Nerve Stimulation.


The relative effects of bretylium, guanethidine and bethanidine on smooth muscle responses to different rates of sympathetic nerve stimulation have been compared. The responses studied were vasoconstriction in the femoral vascular bed and contraction of the spleen in anaesthetized cats, vasoconstriction in perfused ears of rabbits and inhibition of pendular… (More)


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