Comparison of the Analgesic Dose‐Effect Relationships of Nefopam and Oxycodone in Postoperative Pain

@article{Tigerstedt1979ComparisonOT,
  title={Comparison of the Analgesic Dose‐Effect Relationships of Nefopam and Oxycodone in Postoperative Pain},
  author={I. Tigerstedt and Tapani Tammisto and Per Leander},
  journal={Acta Anaesthesiologica Scandinavica},
  year={1979},
  volume={23}
}
The analgesic dose‐effect relationship of nefopam was compared in a double‐blind randomised trial with that of oxycodone in immediate postoperative pain. Nefopam 15 mg or oxycodone 4 mg was given every 10 min i.v. (maximum six times) to patients in pain after upper abdominal surgery until their wound pain (scored 0–3) disappeared. The mean pain intensity (PI), initially 2.2 in both groups, decreased by approximately the same extent for up to two doses in both groups (to 1.5 after nefopam 30 mg… Expand
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
A single slow infusion of nefopam is effective in critically ill patients who have moderate pain and the risk of tachycardia and increased cardiac output and also hypotension and decreased systemic vascular resistance should be known to evaluate the benefit/risk ratio of its prescription. Expand
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TLDR
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Single dose oral oxycodone and oxycodone plus paracetamol (acetaminophen) for acute postoperative pain in adults.
TLDR
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TLDR
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