Comparison of the Analgesic Dose‐Effect Relationships of Nefopam and Oxycodone in Postoperative Pain

  title={Comparison of the Analgesic Dose‐Effect Relationships of Nefopam and Oxycodone in Postoperative Pain},
  author={I. Tigerstedt and T. Tammisto and P. Leander},
  journal={Acta Anaesthesiologica Scandinavica},
  • I. Tigerstedt, T. Tammisto, P. Leander
  • Published 1979
  • Medicine
  • Acta Anaesthesiologica Scandinavica
  • The analgesic dose‐effect relationship of nefopam was compared in a double‐blind randomised trial with that of oxycodone in immediate postoperative pain. Nefopam 15 mg or oxycodone 4 mg was given every 10 min i.v. (maximum six times) to patients in pain after upper abdominal surgery until their wound pain (scored 0–3) disappeared. The mean pain intensity (PI), initially 2.2 in both groups, decreased by approximately the same extent for up to two doses in both groups (to 1.5 after nefopam 30 mg… CONTINUE READING
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