Comparison of tazarotene and minocycline maintenance therapies in acne vulgaris: a multicenter, double-blind, randomized, parallel-group study.

@article{Leyden2006ComparisonOT,
  title={Comparison of tazarotene and minocycline maintenance therapies in acne vulgaris: a multicenter, double-blind, randomized, parallel-group study.},
  author={James J. Leyden and Diane M. Thiboutot and Alan R. Shalita and Guy Webster and Kenneth Washenik and B E Strober and Jerome Shupack},
  journal={Archives of dermatology},
  year={2006},
  volume={142 5},
  pages={605-12}
}
OBJECTIVE To evaluate the efficacy of 3 maintenance regimens (topical tazarotene, oral minocycline hydrochloride, or both) in sustaining improvement in acne. DESIGN Multicenter, open-label treatment phase followed by double-blind, randomized, parallel-group maintenance phase. SETTING Ambulatory patients in research or referral centers. PATIENTS Volunteer sample of 189 patients with moderately severe to severe acne vulgaris (110 entered maintenance phase, 90 completed, and 2 discontinued… CONTINUE READING

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