Comparison of taurine, hypotaurine and β-alanine uptake in brain synaptosomal preparations from developing and adult mouse.

@article{Kontro1984ComparisonOT,
  title={Comparison of taurine, hypotaurine and β-alanine uptake in brain synaptosomal preparations from developing and adult mouse.},
  author={Pirjo Kontro},
  journal={International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience},
  year={1984},
  volume={2 5},
  pages={465-70}
}
The properties of taurine, hypotaurine and β-alanine uptakes were compared in brain synaptosomal preparations from 6-day-old and adult mice. The uptakes of these structurally related amino acids resembled each other, being concentrative, sodium-dependent and inhibited by the same analogues. The absolute sodium requirement of uptake was already evident in developing brain. The affinity of the lowaffinity uptake for taurine was higher in immature than in adult brain. Both affinity and maximal… CONTINUE READING