Comparison of tamarins and marmosets as hosts for GBV-B infections and the effect of immunosuppression on duration of viremia.

@article{Lanford2003ComparisonOT,
  title={Comparison of tamarins and marmosets as hosts for GBV-B infections and the effect of immunosuppression on duration of viremia.},
  author={Robert E. Lanford and Deborah Chavez and Lena Notvall and Kathleen M. Brasky},
  journal={Virology},
  year={2003},
  volume={311 1},
  pages={72-80}
}
GBV-B virus is a close relative to hepatitis C virus (HCV) that causes hepatitis in tamarins, and thus, is an attractive surrogate model for HCV. In this study, we demonstrate that the host range of GBV-B extends to the common marmoset with an infection profile similar to that observed for tamarins. Marmoset hepatocytes were susceptible to in vitro infection with GBV-B. Virus was efficiently secreted into the medium, and approximately 25% of hepatocytes were positive for NS3 staining. In an… CONTINUE READING
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