Comparison of subcutaneous and intraperitoneal injection of d-luciferin for in vivo bioluminescence imaging

@article{Inoue2008ComparisonOS,
  title={Comparison of subcutaneous and intraperitoneal injection of d-luciferin for in vivo bioluminescence imaging},
  author={Yusuke Inoue and Shigeru Kiryu and Katsuhiko Izawa and M. D. Masatoshi Watanabe and Arinobu Tojo and Kouji Ohtomo},
  journal={European Journal of Nuclear Medicine and Molecular Imaging},
  year={2008},
  volume={36},
  pages={771-779}
}
PurposeWe compared subcutaneous (SC) injection and intraperitoneal (IP) injection of d-luciferin for in vivo bioluminescence imaging (BLI) to determine the utility of SC injection.MethodsMice bearing SC tumours stably expressing firefly luciferase underwent in vivo BLI using SC and IP injection of d-luciferin. BLI studies were repeated at an interval of 3 h using a given injection route to assess repeatability and using different injection routes to assess correlation. In mice bearing both SC… CONTINUE READING
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