Comparison of spoligotyping, mycobacterial interspersed repetitive units typing and IS6110-RFLP in a study of genotypic diversity of Mycobacterium tuberculosis in Delhi, North India.

@article{VarmaBasil2011ComparisonOS,
  title={Comparison of spoligotyping, mycobacterial interspersed repetitive units typing and IS6110-RFLP in a study of genotypic diversity of Mycobacterium tuberculosis in Delhi, North India.},
  author={Mandira Varma-Basil and Sujeet Kumar and Jyoti Arora and Archana Angrup and Thierry Zozio and Jayant Nagesh Banavaliker and Urvashi B Singh and Nalin Rastogi and Mridula Bose},
  journal={Memorias do Instituto Oswaldo Cruz},
  year={2011},
  volume={106 5},
  pages={524-35}
}
The aim of the present study was to compare polymerase chain reaction (PCR)-based methods--spoligotyping and mycobacterial interspersed repetitive units (MIRU) typing--with the gold-standard IS6110 restriction fragment length polymorphism (RFLP) analysis in 101 isolates of Mycobacterium tuberculosis to determine the genetic diversity of M. tuberculosis clinical isolates from Delhi, North India. Spoligotyping resulted in 49 patterns (14 clusters); the largest cluster was composed of Spoligotype… CONTINUE READING

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Predominance of a novel Mycobacterium tuberculosis genotype in the Delhi region of India

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Highly Influential
6 Excerpts

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