Comparison of somatosensory evoked potentials and cerebral blood oxygenation changes in the sensorimotor cortex during activation in the rat.

@article{Kondo2010ComparisonOS,
  title={Comparison of somatosensory evoked potentials and cerebral blood oxygenation changes in the sensorimotor cortex during activation in the rat.},
  author={Yuko Kondo and Kaoru Sakatani and Takahiro Igarashi and Tatsuya Hoshino and Yoshihiro Murata and Emiri Tejima and Tsuneo Kano and Yoichi Katayama},
  journal={Advances in experimental medicine and biology},
  year={2010},
  volume={662},
  pages={
          245-9
        }
}
The relationship between changes in cerebral blood oxygenation and neuronal activity remains to be fully established. We compared somatosensory evoked potentials (SEP) and evoked cerebral blood oxygenation (CBO) changes in the sensorimotor cortex of the rat. In rats anesthetized with urethane and alpha-chloralose, we measured SEP and CBO using visible light spectroscopy (VLS) during neuronal activity. Increase of stimulus frequency caused a decrease of SEP amplitude, but an increase in… 
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