Comparison of single-dose diethylcarbamazine and ivermectin for treatment of bancroftian filariasis in Papua New Guinea.

@article{Kazura1993ComparisonOS,
  title={Comparison of single-dose diethylcarbamazine and ivermectin for treatment of bancroftian filariasis in Papua New Guinea.},
  author={James W. Kazura and Joseph Greenberg and Richard Perry and Georges Weil and Karen Day and Michael Alpers},
  journal={The American journal of tropical medicine and hygiene},
  year={1993},
  volume={49 6},
  pages={804-11}
}
This double-blind study compared the clinical safety and parasitologic efficacy of single-dose regimens of diethylcarbamazine (DEC) and ivermectin for treatment of bancroftian filariasis in Papua New Guinea. Five groups of 10 men each with mean levels of parasitemia ranging from 2,985 to 5,185 microfilariae (mf)/ml were given DEC (6 mg/kg of body weight one time or 1 mg/kg, then 6 mg/kg four days later) or ivermectin (220 micrograms/kg; 20 micrograms/kg, then 200 micrograms/kg four days later… CONTINUE READING

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